Coccidiosis is one of the most economically important diseases in poultry production worldwide. It’s caused by protozoan parasites of the genus Eimeria that infect the intestinal tract of broilers, layers and breeders. Here is why it matters so much:

1. The importance of Coccidiosis

   Caused by Eimeria species affecting the intestinal tract
   One of the top causes of economic loss in poultry

   Leads to:
     –  Poor growth and FCR
     –  Reduced egg production
     –  Mortality in severe cases

   Often subclinical, meaning losses occur without obvious signs

2. Why: what’s in it for the farmer?

   –  Better profitability through improved performance
   –  Lower feed costs per kg gain
   –  Reduced mortality and medication costs
   –  Improved uniformity and flock quality
   –  Prevention is cheaper than treatment -> strong ROI

3. Who: Who is immune?

   –  Young birds (0-6 weeks): they are highly susceptible
   –  Older birds -> develop partial immunity after exposure or vaccination

   Immunity is:
   –  Species-specific (one Eimeria species ≠ protection against another)
   –  Dependent on controlled exposure (vaccines or low challenge)
   –  Poor immunity = higher risk of outbreaks

4. When: when does it occur?

   Typically:
   Broilers: 3 – 6 weeks of age. Although it can occur earlier if challenges are high, as chicks have little initial protection.

   Layers/ Breeders: between 3 and 18 weeks of age. Common during rearing as immunity is still developing.

5. Where:

• • The Prevencocci E4 & E7 are manufactured in Argentine pharmaceutical/biotech company focused on avian (poultry) vaccines
  • The company was founded in 1971 by Dr. Raul F. Novella
  • Specializes in development and production of avian vaccines
  • Disease prevention and monitoring in poultry
  • Research & development (R &D) in animal health
  • Produces multiple vaccines targeting major poultry diseases (e.g. coccidiosis, Gumboro)

Prevencocci® Range Overview

Product Variants:

• • Prevencocci® E4
    
    1. Coverage: 4 Eimeria species
    2. Application: Broiler production systems

• • Prevencocci® E7
    
    1. Coverage: 7 Eimeria species
    2. Application: Layers and Breeders

Prevencocci® E4 – For Broilers

• • Targets 4 major Eimeria species
    
    • E.tenella | E.maxima | E.acervulina | E.brunetti

• • Suitable for:
    
    • Broilers

• • Key benefits:
    
    • Maintains gut integrity
    • Supports growth performance
    • Cost effective solution

Main benefits of Prevencocci® E4

• • Better liveweights/ better performance in broilers
  • Better average daily gain (ADG)
  • Better feed conversion ratio (FCR)
  • Lower mortality

Prevencocci® E4 – Mode of Action (Broilers)

• Targets early Eimeria stages in broilers
• disrupts parasite development, limiting multiplication and spread
• Reduces intestinal lesions, preserving gut integrity
• Maintains efficient nutrient absorption and growth rate
• Improves feed conversion ratio (FCR)

Dosage & Administration in Broilers – Prevencocci® E4

• • A single dose (0.0035 ml) of Prevencocci E4 should be administered to chicks in one of the following ways:
    
    • Drinking water: 3 – 5 days
    • Spray over the feed: 3-5 days
  • The minimum dose of vaccine is 0,0035 ml per chick.

Prevencocci® E7 – For Layers & Breeders

• • Targets 7 Eimeria species for layers and breeders
    
    • E.tenella | E.maxima | E.acervulina | E.brunetti |E.mitis | E.necatrix | E.praecox

• • Key benefits:
    
    • Strong protection against outbreaks
    • Reduces lesion severity in layers and breeders
    • Supports consistent egg production and flock performance under coccidial challenge
    • Improves gut integrity and nutrient absorption efficiency
      
      • This will result in better FCR & ADG
      • Lower secondary infections, due to a healthier gut

Main benefits of Prevencocci® E7

• Improved performance parameters
  
  • Better feed conversion ratio (FCR)
  • Improved average daily gain (ADG) during rearing
  • Better live weights and uniformity

• Lower mortality and improved flock health
  
  • Improved gut integrity and resilience
  • Reduces clinical outbreaks

• Supports Antibiotic-free (ABF) programmes
• Stronger immunity for long production cycles
  • • Breeders and layers need lifelong protection, not short-term control
    • Prevencocci® E7 promotes cycling of oocysts -> stronger, lasting immunity
    •  

Prevencocci® E7 – Mode of Action

Controlled exposure to live Eimeria oocysts

• The vaccine contains live, sporulated oocysts of 7 Eimeria species
• After administration (usually spray or drinking water), birds ingest the oocysts

Oocysts shedding and recycling (key mechanism)

• New oocysts are shed in the litter
• Birds re-ingest oocysts through normal pecking behavior

Development of species-specific immunity

• Each Eimeria species stimulates specific immune responses
• Immunity is cell-mediated and localized in the gut

Long-term immunity for production phase

• Through repeated cycling, birds develop robust immunity before point of lay
• Protection throughout the entire laying/breeder cycle

Dosage & Administration – Prevencocci® E7

• Hatchery – course spray or eye drop
• Layers(rearing) – in the drinking water (water fonts) between day 3 and 5
• Breeders – in the drinking water (water fonts) or administered via eye drop

Integration with farm management

Combine with:

• Good litter management
• Biosecurity protocols
• Proper ventilation

Monitor:

• Performance indicators
• Clinical signs

Economic Impact for both Prevencocci® E4 & E7

• Improved production efficiency
• Higher profitability per cycle
• Reduced treatment costs
• Better market weights

Summary of key points

• Coccidiosis remains major production and economic challenge in poultry
• Prevencocci® E4 & E7 provides targeted and effective control solutions
• E4 delivers a high level of protection for broilers
• E7 is specifically designed for layers and breeders